Saturday, July 5, 2008

Saturday July 5, 2008
"estimated average glucose" (or eAG) instead of HbA1c?


Scenario: You admitted 38 year old female with DKA. Looking at her record, you found that her latest "estimated average glucose" reported is 212. What is her estimated HbA1C?

Answer: 9

The HbA1c measures blood glucose control over the previous 90 days. It is expressed as the percent of hemoglobin molecules that have glucose attached. Recommended goal is less than 7% for people with diabetes.


But a new study (soon to be published) has found a simple mathematical formula that can "translate" HbA1c levels into an eAG level. It almost accurately converted HbA1c levels into average glucose levels.


An "estimated average glucose" or eAG is an accurate and easier way to understand glucose control, and probably will soon become the standard of reporting blood glucose control .

Manual way to do formula is

28.7 x HbA1c - 46.7 = eAG (in mg/dl)


Or use following graph
(HbA1C % is followed with both mg/dl and mmol/L values)

6 % = 126 mg/dl = 7.0 mmol/l
6.5% =140 mg/dl = 7.8 mmol/l
7 % = 154 mg/dl = 8.6 mmol/l
7.5 % = 169 mg/dl = 9.4 mmol/l
8 % = 183 mg/dl = 10.1 mmol/l
8.5% = 197 mg/dl = 10.9 mmol/l
9 % = 212 mg/dl = 11.8 mmol/l
9.5 % = 226 mg/dl = 12.6 mmol/l
10 % = 240 mg/dl = 13.4 mmol/l



Reference: Click to get abstract

Translating the A1C Assay Into Estimated Average Glucose Values - Publish Ahead of Print published online ahead of print June 7, 2008, findings will be printed in the August issue of Diabetes Care